41506-14-3

41506-14-3 structure

Name: Nonylbenzene-PEG8-OH
Chemical Name: 1(1-Hydroxy-4,7,10,13,16,19,22-heptaoxa)tetracosyl-4-nonylbenzol
CAS Number: 41506-14-3
Molecular Formula: C₃₁H₅₆O₉
Molecular Weight: 572.77100
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-01 00:52:24
Modify Date: 2025-09-13 12:25:09
Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1(1-Hydroxy-4,7,10,13,16,19,22-heptaoxa)tetracosyl-4-nonylbenzol
Synonyms	2-[2-(2-{2-[2-(2-{2-[2-(4-Nonyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethanol nonylphenol ethoxylate nonylphenyl ethoxyle Igepal BC8

Description	Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562