151978-50-6

151978-50-6 structure

Name: tert-Butyl pent-4-yn-1-ylcarbamate
Chemical Name: N-Boc-4-pentyne-1-amine
CAS Number: 151978-50-6
Molecular Formula: C₁₀H₁₇NO₂
Molecular Weight: 183.24700
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-09-08 10:35:12
Modify Date: 2024-01-11 11:15:14
N-Boc-4-pentyne-1-amine is a PROTAC linker, which refers to the alkyl chain composition. N-Boc-4-pentyne-1-amine can be used in the synthesis of the PROTAC MG-277 (HY-130122)[1].

Name	N-Boc-4-pentyne-1-amine
Synonyms	tert-butyl N-pent-4-ynylcarbamate

Description	N-Boc-4-pentyne-1-amine is a PROTAC linker, which refers to the alkyl chain composition. N-Boc-4-pentyne-1-amine can be used in the synthesis of the PROTAC MG-277 (HY-130122)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
References	[1]. Yang J, et al. Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders. J Med Chem. 2019 Oct 21.

24424-99-5

15252-44-5

~42%

151978-50-6

Literature: WO2013/96771 A1, ; Page/Page column 215 ;

53293-00-8

75-65-0

~85%

151978-50-6

Literature: Synthesis, , # 9 art. no. Z17611SS, p. 1477 - 1483

19596-07-7

151978-50-6

6097-07-0

151978-50-6

Literature: US2011/152321 A1, ;

68275-03-6

151978-50-6

Literature: WO2013/96771 A1, ;

5390-04-5

151978-50-6

Literature: WO2013/96771 A1, ;

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%