503860-57-9
503860-57-9 structure
- Name: SAR502250
- Chemical Name: uda-680
- CAS Number: 503860-57-9
- Molecular Formula: C19H18FN5O2
- Molecular Weight: 367.37700
- Create Date: 2018-04-30 05:27:21
- Modify Date: 2024-01-19 19:01:20
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SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimer’s disease (AD).
| Name | uda-680 |
|---|---|
| Synonyms | 2-[(2S)-2-(2-(4-fluorophenyl)morpholin-4-yl)]-1-methyl-1H-[4,4']bipyrimidinyl-6-one |
| Molecular Formula | C19H18FN5O2 |
|---|---|
| Molecular Weight | 367.37700 |
| Exact Mass | 367.14400 |
| PSA | 73.14000 |
| LogP | 2.01930 |