148404-10-8

148404-10-8 structure

Name: α‑Amylase-IN-1
Chemical Name: 1-[3-(4-Hydroxy-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone
CAS Number: 148404-10-8
Molecular Formula: C₁₈H₁₈N₂O₃
Molecular Weight: 310.35
Catalog: Research Areas Metabolic Disease
Create Date: 2018-05-20 21:06:16
Modify Date: 2024-01-03 11:59:56
α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC50 value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging DPPH free radicals. IC50 can be used in the study of diabetes and oxidative stress-related diseases.[1]

Name	1-[3-(4-Hydroxy-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone

Description	α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC50 value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging DPPH free radicals. IC50 can be used in the study of diabetes and oxidative stress-related diseases.[1]
Related Catalog	Research Areas >> Metabolic Disease
Target	IC50: 0.5509 μM (α-Amylase), 53.49 μM (DPPH)
References	[1]. Ali A, et al. Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure-Activity Relationship, ADMET, and Molecular Docking Studies. ACS Omega. 2023 Jun 2;8(23):20412-20422.