110072-15-6

110072-15-6 structure

Name: TOSAGESTIN
Chemical Name: (17alpha)-17-hydroxy-11-methylene-19-norpregna-4,15-diene-20-yn-3-one
CAS Number: 110072-15-6
Molecular Formula: C₂₁H₂₄O₂
Molecular Weight: 308.41400
Catalog: Research Areas Metabolic Disease
Create Date: 2018-06-27 08:34:11
Modify Date: 2025-09-20 17:05:13
Tosagestin(Org 30659) is a 19-nortestosterone–derived progestagen. Tosagestinsuppresses ovarian function to a level sufficient to inhibit ovulation. Tosagestininhibits cell growth in T47D-S cells[1][2].

Name	(17alpha)-17-hydroxy-11-methylene-19-norpregna-4,15-diene-20-yn-3-one
Synonyms	(17α)-17-hydroxy-11-methylene-19-norpregna-4,15-diene-20-yn-3-one (8R,9S,10R,13S,14S,17R)-17-Ethynyl-17-hydroxy-13-methyl-11-methylene-1,2,6,7,8,9,10,11,12,13,14,17-dodecahydro-cyclopenta[a]phenanthren-3-one [3H]-Tosagestin 17β-hydroxy-11-methylene-19-nor-17α-pregna-4,15-dien-20-yn-3-one Tosagestin 11-methylene-17α-ethinyl-17β-hydroxy-oestra-4,15-dien-3-one (17α)-17-hydroxy-11-methylene-19-norpregna-4, 15-dien-20-yn-3-one

Description	Tosagestin(Org 30659) is a 19-nortestosterone–derived progestagen. Tosagestinsuppresses ovarian function to a level sufficient to inhibit ovulation. Tosagestininhibits cell growth in T47D-S cells[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Schoonen WG, et al. Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines. J Steroid Biochem Mol Biol. 1995;55(3-4):439-444. 、 [2]. Obruca A, et al. Ovarian function during and after treatment with the new progestagen Org 30659. Fertil Steril. 2001;76(1):108-115.