80454-47-3

80454-47-3 structure

Name: euphornin
Chemical Name: euphornin
CAS Number: 80454-47-3
Molecular Formula: C₃₃H₄₄O₉
Molecular Weight: 584.70
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-05-23 18:03:18
Modify Date: 2025-08-26 08:05:53
Euphornin is a anticaner agent, that can be isolated from E. helioscopia. Euphornin induces apoptosis via caspase-mediated pathways. Euphornin induces cell cycle arrest by increasing the level of the phospho-CDK1 (Tyr15) protein[1].

Name	euphornin
Synonyms	Benzoic acid (6E,12E)-(1S,2S,3aR,4S,5S,9R,11R,13aS)-4,9,11-triacetoxy-3a-hydroxy-2,5,8,8,12-pentamethyl-2,3,3a,4,5,8,9,10,11,13a-decahydro-1H-cyclopentacyclododecen-1-yl ester

Description	Euphornin is a anticaner agent, that can be isolated from E. helioscopia. Euphornin induces apoptosis via caspase-mediated pathways. Euphornin induces cell cycle arrest by increasing the level of the phospho-CDK1 (Tyr15) protein[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Caspase
References	[1]. Li XQ, et al. Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest. Onco Targets Ther. 2018 Jul 27;11:4395-4405.