1030846-42-4

1030846-42-4 structure

Name: AS 2034178
Chemical Name: 3-[2-Fluoro-4-({[1-(2-phenoxyethyl)-1,2,3,4-tetrahydro-5-quinolinyl]methyl}amino)phenyl]propanoic acid
CAS Number: 1030846-42-4
Molecular Formula: C₂₇H₂₉FN₂O₃
Molecular Weight: 448.52900
Catalog: Signaling Pathways GPCR/G Protein GPR40
Create Date: 2018-03-14 09:30:58
Modify Date: 2024-01-09 17:22:50
AS2034178 free base, a specific and orally active GPR40 agonist, exhibits glucose-dependent insulin secretion enhancement. AS2034178 free base has potential for type 2 diabetes mellitus research[1].

Name	3-[2-Fluoro-4-({[1-(2-phenoxyethyl)-1,2,3,4-tetrahydro-5-quinolinyl]methyl}amino)phenyl]propanoic acid
Synonyms	Benzenepropanoic acid, 2-fluoro-4-[[[1,2,3,4-tetrahydro-1-(2-phenoxyethyl)-5-quinolinyl]methyl]amino]- 3-[2-Fluoro-4-({[1-(2-phenoxyethyl)-1,2,3,4-tetrahydro-5-quinolinyl]methyl}amino)phenyl]propanoic acid AS2034178

Description	AS2034178 free base, a specific and orally active GPR40 agonist, exhibits glucose-dependent insulin secretion enhancement. AS2034178 free base has potential for type 2 diabetes mellitus research[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GPR40 Research Areas >> Metabolic Disease
References	[1]. Tanaka H, et al. Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion. J Pharmacol Exp Ther. 2013;346(3):443-452.