160214-01-7

160214-01-7 structure

Name: HCV Peptide (35-44)
Chemical Name: Hepatitis C virus core protein(35-44)
CAS Number: 160214-01-7
Molecular Formula: C₅₇H₉₇N₁₉O₁₂
Molecular Weight: 1240.50000
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-06-18 22:06:33
Modify Date: 2024-03-03 16:17:02
HCV Peptide (35-44), a HCV core protein at positions 35 to 44, is a HLA-A2-restricted CTL epitope. HCV Peptide (35-44) inhibits NK cell activity via two distinct mechanisms, directly via KIR2DL2/3, and synergistically via the CD94:NKG2A receptor[1].

Name	Hepatitis C virus core protein(35-44)
Synonyms	C35-44 peptide C 35-44 YLLPRRGPRL peptide C35-44

Description	HCV Peptide (35-44), a HCV core protein at positions 35 to 44, is a HLA-A2-restricted CTL epitope. HCV Peptide (35-44) inhibits NK cell activity via two distinct mechanisms, directly via KIR2DL2/3, and synergistically via the CD94:NKG2A receptor[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	HCV Peptide (35-44) (0-100 μM) 抑制总 NK 细胞群的脱颗粒。 HCV 肽 (35-44) 增加 HLA-C 和 HLA-E 的细胞表面表达[1]。
References	[1]. Cheent KS, et, al. P91 Dual mechanism of NK cell inhibition by the HCV core 35–44 peptide. BMJ journals. 60(Sup 2).