251564-45-1

251564-45-1 structure

Name: Azido-PEG2-C1-Boc
Chemical Name: tert-butyl 8-azido-3,6-dioxaoctanoate
CAS Number: 251564-45-1
Molecular Formula: C₁₀H₁₉N₃O₄
Molecular Weight: 245.27600
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-01-24 02:39:21
Modify Date: 2024-01-09 17:51:22
Azido-PEG2-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	tert-butyl 8-azido-3,6-dioxaoctanoate

Description	Azido-PEG2-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562