Azido-PEG2-C1-Boc

Modify Date: 2024-01-09 17:51:22

Azido-PEG2-C1-Boc Structure
Azido-PEG2-C1-Boc structure
Common Name Azido-PEG2-C1-Boc
CAS Number 251564-45-1 Molecular Weight 245.27600
Density N/A Boiling Point N/A
Molecular Formula C10H19N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG2-C1-Boc


Azido-PEG2-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name tert-butyl 8-azido-3,6-dioxaoctanoate

 Azido-PEG2-C1-Boc Biological Activity

Description Azido-PEG2-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H19N3O4
Molecular Weight 245.27600
Exact Mass 245.13800
PSA 94.51000
LogP 1.12436
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