Top Suppliers:I want be here

71030-36-9

71030-36-9 structure
71030-36-9 structure
  • Name: (±)15-HETE
  • Chemical Name: (+/-)-15-hete
  • CAS Number: 71030-36-9
  • Molecular Formula: C20H32O3
  • Molecular Weight: 320.466
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-03-06 08:53:42
  • Modify Date: 2024-04-02 18:15:43
  • (±)15-HETE is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name (+/-)-15-hete
Synonyms 5,8,11,13-eicosatetraenoic acid, 15-hydroxy-, (5Z,8Z,11Z)-
(5Z,8Z,11Z,13E)-15-Hydroxy-icosa-5,8,11,13-tetraenoic acid
5,8,11,13-Eicosatetraenoic acid, 15-hydroxy-, (5Z,8Z,11Z,13E)-
(5Z,8Z,11Z,13E)-15-Hydroxy-5,8,11,13-icosatetraenoic acid
15-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid
(Z,Z,Z,E)-15-hydroxyeicosa-5,8,11,13-tetraenoic acid
15-hydroxyeicosatetraenoic acid
15-HETE
15-hydroxyeicosa-5Z,8Z,11Z,13E-tetraenoic acid
(5Z,8Z,11Z)-15-hydroxyicosa-5,8,11,13-tetraenoic acid
(15S,5Z,8Z,11Z,13E)-15-hydroxyeicosatetraenoic acid
Description (±)15-HETE is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.0±0.1 g/cm3
Boiling Point 487.7±45.0 °C at 760 mmHg
Molecular Formula C20H32O3
Molecular Weight 320.466
Flash Point 262.8±25.2 °C
Exact Mass 320.235138
PSA 57.53000
LogP 5.22
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.514