18777-73-6

18777-73-6 structure

Name: Sieboldin
Chemical Name: 3-hydroxyphloretin 4'-O-β-D-glucopyranoside
CAS Number: 18777-73-6
Molecular Formula: C₂₁H₂₄O₁₁
Molecular Weight: 452.41
Catalog: Research Areas Metabolic Disease
Create Date: 2018-03-30 12:13:41
Modify Date: 2024-01-02 11:14:08
Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata[1].

Name	3-hydroxyphloretin 4'-O-β-D-glucopyranoside
Synonyms	sieboldin 3-Hydroxyphloretin-4'-β-D-glucosid 3-Hydroxy-phloretin-4'-β-D-glucosid 3-hydroxyphloretin 4'-β-D-glucoside 3-(3,4-Dihydroxy-phenyl)-1-[2,6-dihydroxy-4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-propan-1-one

Description	Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	Others
References	[1]. Kim J H, et al. Trapping of Methylglyoxal by Sieboldin from Malus baccata L. and Identification of Sieboldin-Methylglyoxal Adducts Forms[J]. Natural Product Sciences, 2021, 27(4): 245-250.