Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3β-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranuronosyl)oxy]oleana-12-ene-28-oic acid
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Purity: 98.0%
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80930-74-1

80930-74-1 structure

Name: Zingibroside R1
Chemical Name: 28-O-deglucosyl-chikusetsusaponin V
CAS Number: 80930-74-1
Molecular Formula: C₄₂H₆₆O₁₄
Molecular Weight: 794.96500
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2018-06-10 18:49:09
Modify Date: 2024-01-05 10:57:55
Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity[1].Zingibroside R1 possesses some anti-HIV-1 activity.Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM)[2].

Name	28-O-deglucosyl-chikusetsusaponin V
Synonyms	28-deglucosyl-chikusetsusaponin V Zingibroside R1 polysciassaponin P5 3-O-[O-β-D-glucopyranosyl-(1->2)-(β-D-glucopyranosyluronic acid)]oleanolic acid polysciasaponin P5

Description	Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity[1].Zingibroside R1 possesses some anti-HIV-1 activity.Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM)[2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Research Areas >> Metabolic Disease
Target	IC50: 91.3 μM (2-DG uptake)[1]
References	[1]. Yoshizaki K, et al. Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus). Chem Pharm Bull (Tokyo). 2013;61(3):344-50. Epub 2012 Dec 28 [2]. Hasegawa H, et al. Inhibitory effect of some triterpenoid saponins on glucose transport in tumor cells and its application to in vitro cytotoxic and antiviral activities. Planta Med. 1994 Jun;60 (3):240-3.