86377-52-8

86377-52-8 structure

Name: Ganoderic acid Y
Chemical Name: 3β-hydroxy-5α-lanosta-7,9,24(E)-trien-26-oic acid
CAS Number: 86377-52-8
Molecular Formula: C₃₀H₄₆O₃
Molecular Weight: 454.68400
Catalog: Research Areas Infection
Create Date: 2018-09-24 17:54:26
Modify Date: 2024-01-05 17:41:21
Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating[1][2].

Name	3β-hydroxy-5α-lanosta-7,9,24(E)-trien-26-oic acid
Synonyms	(E)-(R)-6-((3S,5R,10S,13R,14R,17R)-3-Hydroxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-hept-2-enoic acid acide ganoderique Y ganoderic acid Y

Description	Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating[1][2].
Related Catalog	Research Areas >> Infection
In Vitro	Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71[2].
References	[1]. Chen XQ, et al. Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase. Phytochemistry. 2018 May;149:103-115. [2]. Zhang W, et al. Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection. Biochem Biophys Res Commun. 2014 Jul 4;449(3):307-12.

Hazard Codes	Xi