Top Suppliers:I want be here
Related CAS#:
87424-26-8 1314417-95-2
2730-71-4 209810-39-9
35556-06-0 876708-01-9
14097-33-7 448906-49-8
2728373-94-0 183060-99-3
1158522-08-7 940364-43-2
1877349-74-0 134104-43-1
131615-57-1 1334371-08-2
6906-52-1 930439-75-1
1018584-77-4 1375289-11-4

87424-26-8

87424-26-8 structure
87424-26-8 structure
  • Name: Thiocolchicine analog
  • Chemical Name: N-[(7S)-2-hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
  • CAS Number: 87424-26-8
  • Molecular Formula: C21H23NO5S
  • Molecular Weight: 401.47600
  • Create Date: 2017-06-09 09:27:04
  • Modify Date: 2024-01-21 18:26:37
Name N-[(7S)-2-hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Synonyms N-((S)-2-hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide
N-((S)-2-Hydroxy-1,3-dimethoxy-10-methylmercapto-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamid
2-Demethyl Thiocolchicine
COLCHICINE,O(sup 2)-DEMETHYL-10-THIO
(S)-7-Acetylamino-2-hydroxy-1,3-dimethoxy-10-methylmercapto-6,7-dihydro-5H-benzo[a]heptalen-9-on
O(sup 2)-Demethyl-10-thiocolchicine
Density 1.33g/cm3
Boiling Point 766.8ºC at 760 mmHg
Melting Point 218-220ºC
Molecular Formula C21H23NO5S
Molecular Weight 401.47600
Flash Point 417.6ºC
Exact Mass 401.13000
PSA 110.16000
LogP 3.67280
Index of Refraction 1.636

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GH0882000
CHEMICAL NAME :
Colchicine, O(sup 2)-demethyl-10-thio-
CAS REGISTRY NUMBER :
87424-26-8
BEILSTEIN REFERENCE NO. :
3176298
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H23-N-O5-S
MOLECULAR WEIGHT :
401.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intracerebral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
25 ug/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 109,386,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 109,386,1957
Precursor  3

DownStream  0


Chemsrc provides CAS#:87424-26-8 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 87424-26-8 | Chemsrc address: https://m.chemsrc.com/en/baike/1415.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved