Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ((1-((2-AMINO-9H-PURIN-9-YL)METHYL)CYCLOPROPOXY)METHYL)PHOSPHONIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

441785-25-7

441785-25-7 structure

Name: Besifovir
Chemical Name: [1-[(2-aminopurin-9-yl)methyl]cyclopropyl]oxymethylphosphonic acid
CAS Number: 441785-25-7
Molecular Formula: C₁₀H₁₄N₅O₄P
Molecular Weight: 299.223
Catalog: Signaling Pathways Anti-infection HBV
Create Date: 2018-11-29 00:04:24
Modify Date: 2024-01-15 00:25:46
Besifovir (LB80331), a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV) [1][2].

Name	[1-[(2-aminopurin-9-yl)methyl]cyclopropyl]oxymethylphosphonic acid
Synonyms	UNII-4PLG22CQUU [({1-[(2-Amino-9H-purin-9-yl)methyl]cyclopropyl}oxy)methyl]phosphonic acid Besifovir Phosphonic acid, [[[1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl]oxy]methyl]-

Description	Besifovir (LB80331), a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV) [1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV
References	[1]. Jung JA, et al. Pharmacokinetic comparison of the maleate and free base formulations of LB80380, a novel nucleotide analog, in healthy male volunteers. Int J Clin Pharmacol Ther. 2012 Sep;50(9):657-64. [2]. Yuen MF, et al. A randomized placebo-controlled, dose-finding study of oral LB80380 in HBeAg-positive patients with chronic hepatitis B. Antivir Ther. 2006;11(8):977-83.

HS Code	2933990090

693788-86-2

~90%

441785-25-7

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441785-25-7

441784-86-7

441785-25-7

441784-88-9

441785-25-7

441784-84-5

441785-25-7

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%