1271738-74-9
1271738-74-9 structure
- Name: Febuxostat impurity 6
- Chemical Name: Ethyl 2-{3-[(E)-(hydroxyimino)methyl]-4-isobutoxyphenyl}-4-methyl-1,3-thiazole-5-carboxylate
- CAS Number: 1271738-74-9
- Molecular Formula: C18H22N2O4S
- Molecular Weight: 362.443
- Catalog: Research Areas Others
- Create Date: 2018-03-30 08:00:00
- Modify Date: 2023-01-17 22:15:29
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Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].
| Name | Ethyl 2-{3-[(E)-(hydroxyimino)methyl]-4-isobutoxyphenyl}-4-methyl-1,3-thiazole-5-carboxylate |
|---|---|
| Synonyms |
Ethyl 2-{3-[(E)-(hydroxyimino)methyl]-4-isobutoxyphenyl}-4-methyl-1,3-thiazole-5-carboxylate
5-Thiazolecarboxylic acid, 2-[3-[(E)-(hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-, ethyl ester 2-[3-[(Hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid ethyl ester Febuxostat Impurity 10 |
| Description | Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Leonid Metsger, et al. Processes for preparing febuxostat. WO2011031409A1. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 516.9±60.0 °C at 760 mmHg |
| Molecular Formula | C18H22N2O4S |
| Molecular Weight | 362.443 |
| Flash Point | 266.4±32.9 °C |
| Exact Mass | 362.130035 |
| LogP | 5.57 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.583 |
| Water Solubility | Insuluble (6.2E-3 g/L) (25 ºC) |