160552-54-5
160552-54-5 structure
- Name: (R)-Lamivudine sulfoxide
- Chemical Name: 4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
- CAS Number: 160552-54-5
- Molecular Formula: C8H11N3O4S
- Molecular Weight: 245.256
- Create Date: 2018-09-26 17:24:57
- Modify Date: 2025-09-01 09:56:30
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Lamivudine sulfoxide, (R)- is a metabolite of Lamivudine; a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
| Name | 4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone |
|---|---|
| Synonyms |
2(1H)-Pyrimidinone, 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-
4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone 4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone GI 138870X Lamivudine Impurity 8 |
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 601.7±65.0 °C at 760 mmHg |
| Molecular Formula | C8H11N3O4S |
| Molecular Weight | 245.256 |
| Flash Point | 317.7±34.3 °C |
| Exact Mass | 245.047028 |
| LogP | -2.47 |
| Vapour Pressure | 0.0±3.9 mmHg at 25°C |
| Index of Refraction | 1.818 |