(R)-Lamivudine sulfoxide

Modify Date: 2024-04-02 21:23:10

(R)-Lamivudine sulfoxide Structure
(R)-Lamivudine sulfoxide structure
Common Name (R)-Lamivudine sulfoxide
CAS Number 160552-54-5 Molecular Weight 245.256
Density 1.9±0.1 g/cm3 Boiling Point 601.7±65.0 °C at 760 mmHg
Molecular Formula C8H11N3O4S Melting Point N/A
MSDS N/A Flash Point 317.7±34.3 °C

 Use of (R)-Lamivudine sulfoxide


Lamivudine sulfoxide, (R)- is a metabolite of Lamivudine; a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.

 Names

Name 4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 601.7±65.0 °C at 760 mmHg
Molecular Formula C8H11N3O4S
Molecular Weight 245.256
Flash Point 317.7±34.3 °C
Exact Mass 245.047028
LogP -2.47
Vapour Pressure 0.0±3.9 mmHg at 25°C
Index of Refraction 1.818

 Synonyms

2(1H)-Pyrimidinone, 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-
4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
GI 138870X
Lamivudine Impurity 8
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