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321839-75-2

321839-75-2 structure
321839-75-2 structure
  • Name: SSR 125543A
  • Chemical Name: 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-1,3-thiazol-2-amine hydrochloride (1:1)
  • CAS Number: 321839-75-2
  • Molecular Formula: C27H29Cl2FN2OS
  • Molecular Weight: 519.501
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel CFTR
  • Create Date: 2018-03-15 10:44:37
  • Modify Date: 2024-01-12 15:34:18
  • Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research[1].

Name 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-1,3-thiazol-2-amine hydrochloride (1:1)
Synonyms 2-Thiazolamine, 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propyn-1-yl-, hydrochloride (1:1)
4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-1,3-thiazol-2-amine hydrochloride (1:1)
Description Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research[1].
Related Catalog
Target

IC50: CRF1 receptor

References

[1]. Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (CAHtalyst).

Molecular Formula C27H29Cl2FN2OS
Molecular Weight 519.501
Exact Mass 518.136169