199796-52-6
199796-52-6 structure
- Name: DHA-paclitaxel
- Chemical Name: DHA-paclitaxel
- CAS Number: 199796-52-6
- Molecular Formula: C69H81NO15
- Molecular Weight: 1164.38
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
- Create Date: 2018-04-14 19:54:24
- Modify Date: 2025-08-26 23:09:46
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DHA-paclitaxel is an inert prodrug composed of the natural fatty acid DHA covalently linked to the C2'-position of paclitaxel. The paclitaxel moiety binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. Compared to Paclitaxel, DHA-Paclitaxel targets tumor cells more specifically because tumor cells absorb large amounts of natural fatty acids for use as biochemical precursors and energy sources.
| Name | DHA-paclitaxel |
|---|---|
| Synonyms |
PACLITAXEL DOCOSAHEXAENOIC ACID
UNII-OJE5810C4F Taxoprexin DHA-paclitaxel (2α,5β,7β,10β,13α)-4,10-Diacetoxy-13-({(2R,3S)-3-(benzoylamino)-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-docosahexaenoyloxy]-3-phenylpropanoyl}oxy)-1,7-dihydroxy-9-oxo-5,20-epoxytax 
-11-en-2-yl benzoate |
| Description | DHA-paclitaxel is an inert prodrug composed of the natural fatty acid DHA covalently linked to the C2'-position of paclitaxel. The paclitaxel moiety binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. Compared to Paclitaxel, DHA-Paclitaxel targets tumor cells more specifically because tumor cells absorb large amounts of natural fatty acids for use as biochemical precursors and energy sources. |
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| Related Catalog | |
| References |
| Molecular Formula | C69H81NO15 |
|---|---|
| Molecular Weight | 1164.38 |