- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 1-Dehydro-6-gingerdione
- Price: Check
- Purity: 95.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 1-Dehydro-6-gingerdione
- Price: ￥5398.0/10mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: 1-Dehydro-6-gingerdione
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1-Dehydro-6-gingerdione
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
76060-35-0
76060-35-0 structure
- Name: 1-Dehydro-6-gingerdione
- Chemical Name: 1-(4-hydroxy-3-methoxyphenyl)dec-1-ene-3,5-dione
- CAS Number: 76060-35-0
- Molecular Formula: C17H22O4
- Molecular Weight: 290.35400
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2018-12-25 00:09:42
- Modify Date: 2025-08-24 20:21:33
-
6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1].
| Name | 1-(4-hydroxy-3-methoxyphenyl)dec-1-ene-3,5-dione |
|---|---|
| Synonyms |
1-Decene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-
1-(4-Hydroxy-3-methoxyphenyl)-1-decene-3,5-dione [6]-Dehydrogingerdione 1-Dehydro-6-gingerdione |
| Description | 6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 6-Dehydrogingerdione could trigger apoptotic cell death via both mitochondrial- and Fas receptor-mediated pathways[1]. 6-Dehydrogingerdione (6-DG) up-regulates Ser-15 phosphorylation and evoked p53 nuclear translocation[1]. 6-Dehydrogingerdione (6-DG) induces mitochondrial apoptotic pathway[1]. Apoptosis Analysis[1] Cell Line: Hep G2 cells. Concentration: 0, 50, 100 μM. Incubation Time: 24 h. Result: Induced Apoptosis in Hep G2 Cells. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 448.9±40.0 °C at 760 mmHg |
| Molecular Formula | C17H22O4 |
| Molecular Weight | 290.35400 |
| Flash Point | 159.3±20.8 °C |
| Exact Mass | 290.15200 |
| PSA | 63.60000 |
| LogP | 3.52260 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.546 |
|
~%
76060-35-0 |
| Literature: Dennif, Phillip; Macleod, Ian; Whiting, Donald A. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 82 - 87 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |