616884-63-0
616884-63-0 structure
- Name: OMDM-2
- Chemical Name: (9Z)-N-[(2R)-1-Hydroxy-3-(4-hydroxyphenyl)-2-propanyl]-9-octadecenamide
- CAS Number: 616884-63-0
- Molecular Formula: C27H45NO3
- Molecular Weight: 431.651
- Catalog: Research Areas Neurological Disease
- Create Date: 2018-04-20 03:53:50
- Modify Date: 2024-01-10 20:14:49
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OMDM-2 is a potent, selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a Ki of 3.0 μM[1].
| Name | (9Z)-N-[(2R)-1-Hydroxy-3-(4-hydroxyphenyl)-2-propanyl]-9-octadecenamide |
|---|---|
| Synonyms |
(9Z)-N-[(2R)-1-Hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide
9-Octadecenamide, N-[(1R)-2-hydroxy-1-[(4-hydroxyphenyl)methyl]ethyl]-, (9Z)- (9Z)-N-[(2R)-1-Hydroxy-3-(4-hydroxyphenyl)-2-propanyl]-9-octadecenamide |
| Description | OMDM-2 is a potent, selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a Ki of 3.0 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 3.0 μM (anandamide cellular uptake)[1] |
| In Vitro | OMDM-2 shows poor affinity for either CB1 (Ki=5.1 μM) or CB2 (Ki>10 μM) receptors in rat brain and spleen membranes, respectively; OMDM-2 has almost no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC50=10 μM), and no activity as inhibitors of FAAH in N18TG2 cell membranes (Ki>50 μM)[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 625.8±55.0 °C at 760 mmHg |
| Molecular Formula | C27H45NO3 |
| Molecular Weight | 431.651 |
| Flash Point | 332.3±31.5 °C |
| Exact Mass | 431.339935 |
| LogP | 7.76 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.518 |