1472624-85-3
1472624-85-3 structure
- Name: 7ACC2
- Chemical Name: 7-[Benzyl(methyl)amino]-2-oxo-2H-chromene-3-carboxylic acid
- CAS Number: 1472624-85-3
- Molecular Formula: C18H15NO4
- Molecular Weight: 309.316
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Monocarboxylate Transporter
- Create Date: 2018-04-04 10:11:04
- Modify Date: 2024-01-05 19:00:30
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7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells.IC50 value: 11 nM ([14C]-lactate influx) [1]Target: MCT inhibitor; lactate transport inhibitor7ACC2 did not influence the prothrombin time which, together with a good in vitro ADME profile, supports the potential of this new family of compounds to act as anticancer drugs through inhibition of lactate flux.
| Name | 7-[Benzyl(methyl)amino]-2-oxo-2H-chromene-3-carboxylic acid |
|---|---|
| Synonyms |
2H-1-Benzopyran-3-carboxylic acid, 7-[methyl(phenylmethyl)amino]-2-oxo-
7-[Benzyl(methyl)amino]-2-oxo-2H-chromene-3-carboxylic acid 7ACC2 |
| Description | 7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells.IC50 value: 11 nM ([14C]-lactate influx) [1]Target: MCT inhibitor; lactate transport inhibitor7ACC2 did not influence the prothrombin time which, together with a good in vitro ADME profile, supports the potential of this new family of compounds to act as anticancer drugs through inhibition of lactate flux. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 548.9±50.0 °C at 760 mmHg |
| Molecular Formula | C18H15NO4 |
| Molecular Weight | 309.316 |
| Flash Point | 285.8±30.1 °C |
| Exact Mass | 309.100098 |
| LogP | 4.17 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.672 |
| Storage condition | 2-8℃ |