DC Chemicals Limited
China
Product Name: CRANAD-2
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (T-4)-[(1E,6E)-1,7-bis[4-(Dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-?O3,?O5]difluoroboron
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1193447-34-5

1193447-34-5 structure

1193447-34-5 structure

Name: CRANAD-2
Chemical Name: CRANAD-2
CAS Number: 1193447-34-5
Molecular Formula: C₂₃H₂₅BF₂N₂O₂
Molecular Weight: 410.26500
Create Date: 2019-09-21 20:23:59
Modify Date: 2024-01-08 16:31:54
CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM[1][2].

Name	CRANAD-2
Synonyms	(T-4)-[(1E,6E)-1,7-bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-kO3,kO5]difluoro-boron

Description	CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM[1][2].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Ran C, et al. Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits. J Am Chem Soc. 2009 Oct 28;131(42):15257-61. [2]. Ran C, et al. Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species. PLoS One. 2011 Apr 29;6(4):e19362.

Molecular Formula	C₂₃H₂₅BF₂N₂O₂
Molecular Weight	410.26500
Exact Mass	410.19800
PSA	32.78000
LogP	4.93870
Storage condition	2-8°C
Water Solubility	DMSO: soluble 0.2 mg/mL, clear (warmed)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi
RIDADR	NONH for all modes of transport