756526-02-0

756526-02-0 structure

Name: Fmoc-N-amido-PEG8-acid
Chemical Name: Fmoc-NH-PEG8-CH2CH2COOH
CAS Number: 756526-02-0
Molecular Formula: C₃₄H₄₉NO₁₂
Molecular Weight: 663.75200
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-06-21 11:12:02
Modify Date: 2024-01-02 20:01:15
Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Fmoc-NH-PEG8-CH2CH2COOH
Synonyms	5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid Fmoc-N-amido-PEG8-acid

Description	Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244.