Fmoc-N-amido-PEG8-acid

Modify Date: 2024-01-02 20:01:15

Fmoc-N-amido-PEG8-acid Structure
Fmoc-N-amido-PEG8-acid structure
Common Name Fmoc-N-amido-PEG8-acid
CAS Number 756526-02-0 Molecular Weight 663.75200
Density 1.190±0.06 g/cm3 Boiling Point N/A
Molecular Formula C34H49NO12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-N-amido-PEG8-acid


Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Fmoc-NH-PEG8-CH2CH2COOH
Synonym More Synonyms

 Fmoc-N-amido-PEG8-acid Biological Activity

Description Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244.

 Chemical & Physical Properties

Density 1.190±0.06 g/cm3
Molecular Formula C34H49NO12
Molecular Weight 663.75200
Exact Mass 663.32500
PSA 149.47000
LogP 3.52350
Storage condition 2-8°C, Seal
Water Solubility Slightly soluble (2.5 g/L) (25 ºC)

 Synonyms

5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid
Fmoc-N-amido-PEG8-acid
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