1365655-89-5

1365655-89-5 structure

Name: Biotin-PEG2-acid
Chemical Name: 3-{2-[2-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethoxy]ethoxy}propanoic acid
CAS Number: 1365655-89-5
Molecular Formula: C₁₇H₂₉N₃O₆S
Molecular Weight: 403.494
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-05-06 12:23:14
Modify Date: 2024-01-02 20:35:07
Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	3-{2-[2-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethoxy]ethoxy}propanoic acid
Synonyms	Propanoic acid, 3-[2-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]- 3-{2-[2-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethoxy]ethoxy}propanoic acid

Description	Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Inflammation/Immunology
Target	Non-cleavable
In Vitro	Biotin-PEG2-acid is used to cap the N-terminus of the peptide while the peptide was still attached to the resin[1].
References	[1]. Merg AD, et al. Seeded Heteroepitaxial Growth of Crystallizable Collagen Triple Helices: Engineering Multifunctional Two-Dimensional Core-Shell Nanostructures. J Am Chem Soc. 2019 Dec 26;141(51):20107-20117.