1271728-79-0

1271728-79-0 structure

Name: Azido-PEG2-C2-Boc
Chemical Name: 2-Methyl-2-propanyl 3-[2-(2-azidoethoxy)ethoxy]propanoate
CAS Number: 1271728-79-0
Molecular Formula: C₁₁H₂₁N₃O₄
Molecular Weight: 259.302
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-05 08:57:28
Modify Date: 2024-01-08 12:01:49
Azido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-Methyl-2-propanyl 3-[2-(2-azidoethoxy)ethoxy]propanoate
Synonyms	Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-, 1,1-dimethylethyl ester 2-Methyl-2-propanyl 3-[2-(2-azidoethoxy)ethoxy]propanoate

Description	Azido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562