Azido-PEG2-C2-Boc

Modify Date: 2024-01-08 12:01:49

Azido-PEG2-C2-Boc Structure
Azido-PEG2-C2-Boc structure
Common Name Azido-PEG2-C2-Boc
CAS Number 1271728-79-0 Molecular Weight 259.302
Density N/A Boiling Point N/A
Molecular Formula C11H21N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG2-C2-Boc


Azido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl 3-[2-(2-azidoethoxy)ethoxy]propanoate
Synonym More Synonyms

 Azido-PEG2-C2-Boc Biological Activity

Description Azido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H21N3O4
Molecular Weight 259.302
Exact Mass 259.153198
LogP 1.34

 Synonyms

Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 3-[2-(2-azidoethoxy)ethoxy]propanoate