172646-47-8

172646-47-8 structure

Name: 5,5'-Dinitro BAPTA AM
Chemical Name: 5,5'-Dinitro BAPTA, AM [1,2-Bis(2-AMino-5-nitrophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxyMethyl) ester]
CAS Number: 172646-47-8
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Others
Create Date: 2018-06-30 07:47:53
Modify Date: 2024-06-24 01:22:19
5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].

Name	5,5'-Dinitro BAPTA, AM [1,2-Bis(2-AMino-5-nitrophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxyMethyl) ester]

Description	5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	5,5'-Dinitro BAPTA AM (50 μM; 20 min) attenuates evoked field excitatory postsynaptic potentials[1].
References	[1]. Ouanounou A, et al. Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 1996 Nov;75(1):99-109.

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