5,5'-Dinitro BAPTA AM

Modify Date: 2024-06-24 01:22:19

5,5'-Dinitro BAPTA AM Structure
5,5'-Dinitro BAPTA AM structure
Common Name 5,5'-Dinitro BAPTA AM
CAS Number 172646-47-8 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5,5'-Dinitro BAPTA AM


5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].

 Names

Name 5,5'-Dinitro BAPTA, AM [1,2-Bis(2-AMino-5-nitrophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxyMethyl) ester]

 5,5'-Dinitro BAPTA AM Biological Activity

Description 5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].
Related Catalog
In Vitro 5,5'-Dinitro BAPTA AM (50 μM; 20 min) attenuates evoked field excitatory postsynaptic potentials[1].
References

[1]. Ouanounou A, et al. Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 1996 Nov;75(1):99-109.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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