217176-83-5

217176-83-5 structure

Name: Dihydrorhodamine 6G
Chemical Name: DHR 6G [DihydrorhodaMine 6G]
CAS Number: 217176-83-5
Molecular Formula: C₂₈H₃₂N₂O₃
Molecular Weight: 444.565
Catalog: Research Areas Cancer
Create Date: 2018-02-23 17:12:23
Modify Date: 2024-01-07 20:00:29
Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide[1].

Name	DHR 6G [DihydrorhodaMine 6G]
Synonyms	Benzoic acid, 2-[3,6-bis(ethylamino)-2,7-dimethyl-9H-xanthen-9-yl]-, ethyl ester Ethyl 2-[3,6-bis(ethylamino)-2,7-dimethyl-9H-xanthen-9-yl]benzoate

Description	Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Yong Qin, et al. Dihydrorhodamine 123 is superior to 2,7-dichlorodihydrofluorescein diacetate and dihydrorhodamine 6G in detecting intracellular hydrogen peroxide in tumor cells. Cell Biol Int. 2008 Feb;32(2):224-8.