Dihydrorhodamine 6G

Modify Date: 2024-01-07 20:00:29

Dihydrorhodamine 6G Structure
Dihydrorhodamine 6G structure
Common Name Dihydrorhodamine 6G
CAS Number 217176-83-5 Molecular Weight 444.565
Density 1.2±0.1 g/cm3 Boiling Point 572.4±50.0 °C at 760 mmHg
Molecular Formula C28H32N2O3 Melting Point N/A
MSDS N/A Flash Point 300.0±30.1 °C

 Use of Dihydrorhodamine 6G


Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide[1].

 Names

Name DHR 6G [DihydrorhodaMine 6G]
Synonym More Synonyms

 Dihydrorhodamine 6G Biological Activity

Description Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide[1].
Related Catalog
References

[1]. Yong Qin, et al. Dihydrorhodamine 123 is superior to 2,7-dichlorodihydrofluorescein diacetate and dihydrorhodamine 6G in detecting intracellular hydrogen peroxide in tumor cells. Cell Biol Int. 2008 Feb;32(2):224-8.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 572.4±50.0 °C at 760 mmHg
Molecular Formula C28H32N2O3
Molecular Weight 444.565
Flash Point 300.0±30.1 °C
Exact Mass 444.241302
LogP 6.95
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.625

 Synonyms

Benzoic acid, 2-[3,6-bis(ethylamino)-2,7-dimethyl-9H-xanthen-9-yl]-, ethyl ester
Ethyl 2-[3,6-bis(ethylamino)-2,7-dimethyl-9H-xanthen-9-yl]benzoate