60748-45-0

60748-45-0 structure

Name: ATX-II
Chemical Name: Toxin Ⅱ,Anemonia sulcata
CAS Number: 60748-45-0
Molecular Formula: C₂₁₃H₃₂₃N₆₃O₆₁S₆
Molecular Weight:
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2018-08-25 09:09:23
Modify Date: 2024-01-02 14:16:06
ATX-II is a specific Na+ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na+HY-B1010), Caffeine, and Ryanodine (HY-103306). ATX-II also induces pulmonary vein arrhythmogenesis and atrial fibrillation[1][2].

Name	Toxin Ⅱ,Anemonia sulcata

Description	ATX-II is a specific Na+ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na+HY-B1010), Caffeine, and Ryanodine (HY-103306). ATX-II also induces pulmonary vein arrhythmogenesis and atrial fibrillation[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Inflammation/Immunology
References	[1]. Fletcher JE, et al. ATX II, a sodium channel toxin, sensitizes skeletal muscle to halothane, caffeine, and ryanodine. Anesthesiology. 1999 May;90(5):1294-301. [2]. Lu YY, et al. ATX-II-induced pulmonary vein arrhythmogenesis related to atrial fibrillation and long QT syndrome. Eur J Clin Invest. 2012 Aug;42(8):823-31.

Molecular Formula	C₂₁₃H₃₂₃N₆₃O₆₁S₆