42616-25-1

42616-25-1 structure

Name: L-Methionine γ-lyase
Chemical Name: L- Methionineγ-Lyase
CAS Number: 42616-25-1
Molecular Formula: C₉H₁₄N₂O₁₂P₂
Molecular Weight: 404.161182
Catalog: Biochemical Amino acids and their derivatives Methionine derivatives
Create Date: 2019-03-20 16:30:36
Modify Date: 2025-08-26 16:01:28
L-Methionine γ-lyase (Methionine lyase) is a multifunctional enzyme, which belongs to the γ-family of pyridoxal-5’-phosphate (PLP) dependent enzyme. L-Methionine γ-lyase can catylyse α, γ-elimunation of L-methionine and homocysteine. L-Methionine γ-lyase has anticancer and anti-infectious activity, and also can be used for homocysteinemia study[1][2][3].

Name	L- Methionineγ-Lyase

Description	L-Methionine γ-lyase (Methionine lyase) is a multifunctional enzyme, which belongs to the γ-family of pyridoxal-5’-phosphate (PLP) dependent enzyme. L-Methionine γ-lyase can catylyse α, γ-elimunation of L-methionine and homocysteine. L-Methionine γ-lyase has anticancer and anti-infectious activity, and also can be used for homocysteinemia study[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Hendy MH, et al. Purification, Characterization and anticancer activity of L-methionine γ-lyase from thermo-tolerant Aspergillus fumigatus. Microb Cell Fact. 2023;22(1):8. [2]. Machover D, et al. Effects in Cancer Cells of the Recombinant l-Methionine Gamma-Lyase from Brevibacterium aurantiacum. Encapsulation in Human Erythrocytes for Sustained l-Methionine Elimination. J Pharmacol Exp Ther. 2019;369(3):489-502. doi:10.1124/jpet.119.256537 [3]. Yoshimura M, et al. Formation of methyl mercaptan from L-methionine by Porphyromonas gingivalis. Infect Immun. 2000;68(12):6912-6916.