L-Methionine γ-lyase

Modify Date: 2024-01-03 10:24:27

L-Methionine γ-lyase structure	Common Name	L-Methionine γ-lyase
	CAS Number	42616-25-1	Molecular Weight	404.161182
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₄N₂O₁₂P₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of L-Methionine γ-lyase

L-Methionine γ-lyase (Methionine lyase) is a multifunctional enzyme, which belongs to the γ-family of pyridoxal-5’-phosphate (PLP) dependent enzyme. L-Methionine γ-lyase can catylyse α, γ-elimunation of L-methionine and homocysteine. L-Methionine γ-lyase has anticancer and anti-infectious activity, and also can be used for homocysteinemia study[1][2][3].

Name	L- Methionineγ-Lyase

Description	L-Methionine γ-lyase (Methionine lyase) is a multifunctional enzyme, which belongs to the γ-family of pyridoxal-5’-phosphate (PLP) dependent enzyme. L-Methionine γ-lyase can catylyse α, γ-elimunation of L-methionine and homocysteine. L-Methionine γ-lyase has anticancer and anti-infectious activity, and also can be used for homocysteinemia study[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Hendy MH, et al. Purification, Characterization and anticancer activity of L-methionine γ-lyase from thermo-tolerant Aspergillus fumigatus. Microb Cell Fact. 2023;22(1):8. [2]. Machover D, et al. Effects in Cancer Cells of the Recombinant l-Methionine Gamma-Lyase from Brevibacterium aurantiacum. Encapsulation in Human Erythrocytes for Sustained l-Methionine Elimination. J Pharmacol Exp Ther. 2019;369(3):489-502. doi:10.1124/jpet.119.256537 [3]. Yoshimura M, et al. Formation of methyl mercaptan from L-methionine by Porphyromonas gingivalis. Infect Immun. 2000;68(12):6912-6916.

Description

Related Catalog

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Hendy MH, et al. Purification, Characterization and anticancer activity of L-methionine γ-lyase from thermo-tolerant Aspergillus fumigatus. Microb Cell Fact. 2023;22(1):8.

[2]. Machover D, et al. Effects in Cancer Cells of the Recombinant l-Methionine Gamma-Lyase from Brevibacterium aurantiacum. Encapsulation in Human Erythrocytes for Sustained l-Methionine Elimination. J Pharmacol Exp Ther. 2019;369(3):489-502. doi:10.1124/jpet.119.256537

[3]. Yoshimura M, et al. Formation of methyl mercaptan from L-methionine by Porphyromonas gingivalis. Infect Immun. 2000;68(12):6912-6916.

Molecular Formula	C₉H₁₄N₂O₁₂P₂
Molecular Weight	404.161182
Storage condition	−20°C

L-Methionine γ-lyase

Use of L-Methionine γ-lyase

Names

L-Methionine γ-lyase Biological Activity

Chemical & Physical Properties