Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Thiol-PEG5-alcohol
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Purity: 95.0%
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248582-03-8

248582-03-8 structure

248582-03-8 structure

Name: Thiol-PEG5-alcohol
Chemical Name: Thiol-PEG5-alcohol
CAS Number: 248582-03-8
Molecular Formula: C₁₀H₂₂O₅S
Molecular Weight: 254.341
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-02-06 04:37:55
Modify Date: 2024-09-15 10:09:57
Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Thiol-PEG5-alcohol
Synonyms	2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethanol HS-PEG5-OH

Description	Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₀H₂₂O₅S
Molecular Weight	254.341

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