Thiol-PEG5-alcohol

Modify Date: 2023-01-15 07:32:03

Thiol-PEG5-alcohol structure	Common Name	Thiol-PEG5-alcohol
	CAS Number	248582-03-8	Molecular Weight	254.341
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₂₂O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thiol-PEG5-alcohol

Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Thiol-PEG5-alcohol
Synonym	More Synonyms

Description	Thiol-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₀H₂₂O₅S
Molecular Weight	254.341

2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethanol

HS-PEG5-OH