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  • DC Chemicals Limited
  • China
  • Product Name: GX-674
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1432913-36-4

1432913-36-4 structure
1432913-36-4 structure
  • Name: GX-674
  • Chemical Name: GX674
  • CAS Number: 1432913-36-4
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
  • Create Date: 2018-02-15 01:24:35
  • Modify Date: 2023-01-14 16:57:00
  • GX-674 is a potent, state-dependent, isoform-selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 of 0.1 nM at -40 mV[1].

Name GX674
Description GX-674 is a potent, state-dependent, isoform-selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 of 0.1 nM at -40 mV[1].
Related Catalog
Target

hNav1.7:0.1 nM (IC50)

References

[1]. Ahuja S, et al. Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist. Science. 2015 Dec 18;350(6267):aac5464.

No Any Chemical & Physical Properties