GX-674

Modify Date: 2023-01-14 16:57:00

GX-674 Structure
GX-674 structure
Common Name GX-674
CAS Number 1432913-36-4 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GX-674


GX-674 is a potent, state-dependent, isoform-selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 of 0.1 nM at -40 mV[1].

 Names

Name GX674

 GX-674 Biological Activity

Description GX-674 is a potent, state-dependent, isoform-selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 of 0.1 nM at -40 mV[1].
Related Catalog
Target

hNav1.7:0.1 nM (IC50)

References

[1]. Ahuja S, et al. Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist. Science. 2015 Dec 18;350(6267):aac5464.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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