403848-57-7
403848-57-7 structure
- Name: Caspase-9 Inhibitor III
- Chemical Name: Ac-Leu-Glu-His-Asp-chloromethylketone
- CAS Number: 403848-57-7
- Molecular Formula: C24H35ClN6O9
- Molecular Weight: 587.02
- Catalog: Signaling Pathways Apoptosis Caspase
- Create Date: 2018-05-21 08:00:00
- Modify Date: 2025-08-25 11:12:51
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Caspase-9 Inhibitor III (Ac-LEHD-cmk) is a caspase-9 inhibitor. Caspase-9 Inhibitor III exhibits protective effects on ischemia-reperfusion-induced myocardial injury[1].
| Name | Ac-Leu-Glu-His-Asp-chloromethylketone |
|---|---|
| Synonyms |
Caspase-9 Inhibitor III
AC-LEHD-CMK |
| Description | Caspase-9 Inhibitor III (Ac-LEHD-cmk) is a caspase-9 inhibitor. Caspase-9 Inhibitor III exhibits protective effects on ischemia-reperfusion-induced myocardial injury[1]. |
|---|---|
| Related Catalog | |
| Target |
Caspase-9 |
| In Vitro | Caspase-9 Inhibitor III (0.07-0.105 μM; 灌注 10 min) 显着减弱 I/R 诱导的离体大鼠心脏梗塞大小的增加，冠状动脉废水中乳酸脱氢酶的释放和肌酸激酶的释放，以及凋亡指数[1]。 Caspase-9 Inhibitor III (30 μM) 抑制由 MMP-2 诱导的肌钙蛋白 I 水解[2]。 |
| References |
| Molecular Formula | C24H35ClN6O9 |
|---|---|
| Molecular Weight | 587.02 |