1159588-21-2

1159588-21-2 structure

Name: (Z)-Pitavastatin calcium
Chemical Name: (Z)-Pitavastatin Calcium Salt
CAS Number: 1159588-21-2
Molecular Formula: C₅₀H₄₆CaF₂N₂O₈
Molecular Weight: 881.0
Catalog: Research Areas Others
Create Date: 2018-12-18 18:13:49
Modify Date: 2026-07-16 11:03:29
(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].

Name	(Z)-Pitavastatin Calcium Salt
Synonyms	Pitavastatin Impurity 5

Description	(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor.Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.