(Z)-Pitavastatin calcium

Modify Date: 2024-01-03 15:26:59

(Z)-Pitavastatin calcium Structure
(Z)-Pitavastatin calcium structure
Common Name (Z)-Pitavastatin calcium
CAS Number 1159588-21-2 Molecular Weight 420.4528232
Density N/A Boiling Point N/A
Molecular Formula C25H24FNO4.1/2Ca Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (Z)-Pitavastatin calcium


(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].

 Names

Name (Z)-Pitavastatin Calcium Salt
Synonym More Synonyms

 (Z)-Pitavastatin calcium Biological Activity

Description (Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].
Related Catalog
References

[1]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor.Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.

 Chemical & Physical Properties

Molecular Formula C25H24FNO4.1/2Ca
Molecular Weight 420.4528232

 Synonyms

Pitavastatin Impurity 5
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