1000690-85-6
1000690-85-6 structure
- Name: Tilapertin
- Chemical Name: Tilapertin
- CAS Number: 1000690-85-6
- Molecular Formula: C20H21F3N2O2
- Molecular Weight: 378.388
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel GlyT
- Create Date: 2018-02-25 22:10:19
- Modify Date: 2025-08-21 18:08:50
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Tilapertin is an oral inhibitor of glycine transporter type-1 (GlyT1).
| Name | Tilapertin |
|---|---|
| Synonyms |
(4-{(R)-Phenyl[3-(trifluoromethyl)phenyl]methyl}-1-piperazinyl)acetic acid
tilapertin 1-Piperazineacetic acid, 4-[(R)-phenyl[3-(trifluoromethyl)phenyl]methyl]- A2SV488G98 |
| Description | Tilapertin is an oral inhibitor of glycine transporter type-1 (GlyT1). |
|---|---|
| Related Catalog | |
| Target |
GlyT1[1] |
| In Vivo | Tilapertin is a nanomolar potent, orally bioavailable and selective GlyT1 inhibitor. Oral administration of Tilapertin dose-dependently increases cerebrospinal fluid (CSF) glycine concentration in rats[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 455.3±45.0 °C at 760 mmHg |
| Molecular Formula | C20H21F3N2O2 |
| Molecular Weight | 378.388 |
| Flash Point | 229.2±28.7 °C |
| Exact Mass | 378.155518 |
| LogP | 2.95 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.554 |
| Storage condition | 2-8℃ |