1321546-70-6

1321546-70-6 structure

Name	(S)-(-)-5-Fluorowillardiine hydrochloride
Synonyms	L-Alanine, 3-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-, hydrochloride (1:1) 3-(5-Fluoro-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-L-alanine hydrochloride (1:1) (S)-(-)-5-Fluorowillardiine (hydrochloride)

Description	(S)-(-)-5-Fluorowillardiine Hcl is a potent and specific AMPAR agonist.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease
References	[1]. Hawkinson JE, et al. Effects of thiocyanate and AMPA receptor ligands on (S)-5-fluorowillardiine, (S)-AMPA and (R,S)-AMPA binding. Eur J Pharmacol. 1997 Jun 25;329(2-3):213-21. [2]. Kessler M, et al. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain Res. 2006 Mar 3;1076(1):25-41. [3]. Rembach A, et al. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS. J Neurosci Res. 2004 Aug 15;77(4):573-82.