171543-83-2
171543-83-2 structure
- Name: Urocortin rat
- Chemical Name: Urocortin, rat
- CAS Number: 171543-83-2
- Molecular Formula: C206H338N62O64
- Molecular Weight: 4707.26
- Catalog: Peptides
- Create Date: 2018-01-11 08:06:18
- Modify Date: 2025-08-25 07:48:55
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Urocortin, rat is a selective agonist of CRF receptor, with Kis of 0.32, 2.2, and 0.62 nM for hCRF1, rCRF2α and mCRF2β, respectively.
| Name | Urocortin, rat |
|---|
| Description | Urocortin, rat is a selective agonist of CRF receptor, with Kis of 0.32, 2.2, and 0.62 nM for hCRF1, rCRF2α and mCRF2β, respectively. |
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| Related Catalog | |
| Target |
Ki: 0.32 nM (hCRF1), 2.2 nM (rCRF2α), and 0.62 nM (mCRF2β)[1] |
| In Vitro | Urocortin, rat is a selective agonist of CRF receptor, with Kis of 0.32, 2.2, and 0.62 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively[1]. |
| In Vivo | Urocortin (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such a effect also observed in mice after 1 μg of Urocortin i.c.v. administration. Urocortin has the potential of inducing anxiogenic behavior[2]. |
| References |
[2]. Skelton KH, et al. The neurobiology of urocortin. Regul Pept. 2000 Sep 25;93(1-3):85-92. |
| Molecular Formula | C206H338N62O64 |
|---|---|
| Molecular Weight | 4707.26 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |