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171543-83-2

171543-83-2 structure

171543-83-2 structure

Name: Urocortin rat
Chemical Name: Urocortin, rat
CAS Number: 171543-83-2
Molecular Formula: C₂₀₆H₃₃₈N₆₂O₆₄
Molecular Weight: 4707.26
Catalog: Peptides
Create Date: 2018-01-11 08:06:18
Modify Date: 2026-08-06 10:52:33
Urocortin, rat is a selective agonist of CRF receptor, with Kis of 0.32, 2.2, and 0.62 nM for hCRF1, rCRF2α and mCRF2β, respectively.

Name	Urocortin, rat
Synonyms	UROCORTIN (RAT) UROCORTIN (RAT) (FREE ACID) UROCORTIN (RAT) (MOUSE) Urocortin ratUrocortin Urocortin rat >= (HPLC), powder Urocortin (she Urocortin rat, (HPLC) H-ASP-ASP-PRO-PRO-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-G-THR-LEU-LEU-GLU-LEU-ALA-G-THR-GLN-SER-GLN-G-GLU-G-ALA-GLU-GLN-ASN-G-ILE-ILE-PHE-ASP-SER-VAL-OH Urocortin 1 (rat) Urocortin (rat) (trifluoroacetate salt) ASP-ASP-PRO-PRO-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-G-THR-LEU-LEU-GLU-LEU-ALA-G-THR-GLN-SER-GLN-G-GLU-G-ALA-GLU-GLN-ASN-G-ILE-ILE-PHE-ASP-SER-VAL Rat urocortin DDPPLSIDLTFHLTLLELTQSQRERAEQNRIIFDSV-NH2 Urocortin(Rattus norvegicus) (9CI) C206H338N62O64 Urocortin (Rattus norvegicus) ASP-ASP-PRO-PRO-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-G-THR-LEU-LEU-GLU-LEU-ALA-G-THR-GLN-SER-GLN-G-GLU-G-ALA-GLU-GLN-ASN-G-ILE-ILE-PHE-ASP-SER-VAL-NH2 PubChem ID H-ASP-ASP-PRO-PRO-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-G-THR-LEU-LEU-GLU-LEU-ALA-G-THR-GLN-SER-GLN-G-GLU-G-ALA-GLU-GLN-ASN-G-ILE-ILE-PHE-ASP-SER-VAL-NH2

Description	Urocortin, rat is a selective agonist of CRF receptor, with Kis of 0.32, 2.2, and 0.62 nM for hCRF1, rCRF2α and mCRF2β, respectively.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CRFR Research Areas >> Neurological Disease Peptides
Target	Ki: 0.32 nM (hCRF1), 2.2 nM (rCRF2α), and 0.62 nM (mCRF2β)[1]
In Vitro	Urocortin, rat is a selective agonist of CRF receptor, with Kis of 0.32, 2.2, and 0.62 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively[1].
In Vivo	Urocortin (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such a effect also observed in mice after 1 μg of Urocortin i.c.v. administration. Urocortin has the potential of inducing anxiogenic behavior[2].
References	[1]. Reul JM, et al. Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr Opin Pharmacol. 2002 Feb;2(1):23-33. [2]. Skelton KH, et al. The neurobiology of urocortin. Regul Pept. 2000 Sep 25;93(1-3):85-92.

Molecular Formula	C₂₀₆H₃₃₈N₆₂O₆₄
Molecular Weight	4707.26

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