1817626-54-2

1817626-54-2 structure

Name: PF06650833
Chemical Name: PF06650833
CAS Number: 1817626-54-2
Molecular Formula: C₁₈H₂₀FN₃O₄
Molecular Weight: 361.367
Catalog: Signaling Pathways Immunology/Inflammation IRAK
Create Date: 2018-03-30 12:14:29
Modify Date: 2025-08-21 11:47:43
PF06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), and used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas.

Name	PF06650833
Synonyms	1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxo-2-pyrrolidinyl]methoxy}-7-methoxy-6-isoquinolinecarboxamide S3F315JJXI 6-Isoquinolinecarboxamide, 1-[[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxo-2-pyrrolidinyl]methoxy]-7-methoxy-

Description	PF06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), and used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> IRAK Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IRAK Research Areas >> Inflammation/Immunology
References	[1]. Seganish WM. Inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4): a patent review (2012-2015). Expert Opin Ther Pat. 2016 Aug;26(8):917-32.