501921-61-5
501921-61-5 structure
- Name: Entasobulin
- Chemical Name: Entasobulin
- CAS Number: 501921-61-5
- Molecular Formula: C26H18ClN3O2
- Molecular Weight: 439.893
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
- Create Date: 2018-02-16 16:44:28
- Modify Date: 2025-09-15 22:29:55
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Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity.
| Name | Entasobulin |
|---|---|
| Synonyms |
2-[1-(4-chlorobenzyl)-1H-indol-3-yl]-2-oxo-N-(quinolin-6-yl)acetamide
1H-Indole-3-acetamide, 1-[(4-chlorophenyl)methyl]-α-oxo-N-6-quinolinyl- entasobulin TB77GU6BFO 2-[1-(4-Chlorobenzyl)-1H-indol-3-yl]-2-oxo-N-(6-quinolinyl)acetamide |
| Description | Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity. |
|---|---|
| Related Catalog | |
| Target |
β-tubulin polymerization |
| In Vitro | Entasobulin is a indolizine-glyoxylamide based small molecule that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C26H18ClN3O2 |
| Molecular Weight | 439.893 |
| Exact Mass | 439.108765 |
| LogP | 5.36 |
| Index of Refraction | 1.683 |
| Storage condition | 2-8℃ |