137004-80-9

137004-80-9 structure
137004-80-9 structure

Name CCK-A receptor inhibitor 1
Description CCK-A receptor inhibitor 1 is a cholecystokinin A (CCK-A) receptor inhibitor with a binging IC50 of 340 nM.
Related Catalog
Target

IC50: 340 nM (CCK-A receptor)[1]

In Vitro CCK-A receptor inhibitor 1 (Compound 7c) is a naphthyl sulfone derivative, which is synthesized and tested for cholecystokinin A (CCK-A) receptor inhibitory activity in order to study structure-activity relationships. Significant CCK-A receptor inhibitory activities are found in CCK-A receptor inhibitor 1 having very hydrophobic sidechains[1].
References

[1]. Ajisawa Y, et al. [Studies on the synthesis of cholecystokinin A receptor antagonists. III. Synthesis and cholecystokinin A receptor inhibitory activities of naphthyl sulfone derivatives]. Yakugaku Zasshi. 1996 Aug;116(8):647-56.

Molecular Formula C25H35NO6S
Molecular Weight 477.61
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